The 2015 Big 12 Conference football season is the 20th season of college football play for the Big 12 Conference. It is part of the 2015 NCAA Division I FBS football season.
Conference play began on October 3, 2015 with a 44–24 win against West Virginia in Norman, Oklahoma and ended with a 58–23 win against Oklahoma State in Stillwater, Oklahoma on November 28, 2015. Oklahoma finished conference play with a 8–1 record winning their ninth Big 12 Championship, their first since 2012.
Oklahoma was selected as the 4th seed to play in the 2015 College Football playoff against 1st seed Clemson on December 31, 2015 in the Orange Bowl which they lost 17–37. Oklahoma finished the season with an 11–2 record.